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br Introduction Coping with DNA damage is possible
2019-09-16
Introduction Coping with DNA damage is possible thanks to surveillance mechanisms (checkpoints), that detect the problem and promote its solution [1], [2], and to repair and tolerance pathways that remove the lesions or reduce the damage consequences [3], [4]. Failures in these processes have a h
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The results described in the present study confirm key restr
2019-09-16
The results described in the present study confirm key restrictions on reaction conditions which must considered to maximize reactor productivity. Increased viscosity should be avoided for the amination of ketones by L-AmDH, as a 4-fold increase in viscosity can lower the reaction rate by as much as
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In this review focusing on biocatalyst
2019-09-16
In this review, focusing on biocatalyst “formate dehydrogenase FDH” catalyzing both of the formic Calyculin A oxidation to CO2 and the CO2 reduction to formic acid, representative examples of properties, types, structure of active-site of FDH and, reaction mechanism of formic acid oxidation and CO2
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br Prospect of DDR antagonist
2019-09-16
Prospect of DDR2 antagonist DDR2, a receptor of tyrosine kinase has been found now to be reported to play a significant role in onset of osteoarthritis at the early stage of diseases progression. The DDR2 are the receptor for extracellular collagen and activated upon the binding of collagen resul
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Interaction between neutrophils and ECs represents
2019-09-16
Interaction between neutrophils and ECs represents the first step of the cellular phase of the inflammatory response, and provide the best condition for the transfer of the PMNL-derived LTA4 to the ECs, leading to the transcellular formation of cysteinyl-LTs. It is intriguing therefore to think that
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It is now widely known that blockade of
2019-09-16
It is now widely known that blockade of CysLT1 receptors strongly inhibits antigen-induced bronchial contractions in specimens isolated from non-asthma subjects. However, this blockade is not complete as shown in the present study and in other literature.4, 15, 16 The results of the current study su
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Neutrophils produce high amounts of ROS which
2019-09-12
Neutrophils produce high amounts of ROS, which act as antimicrobial agents, signaling molecules or initiators during PMA-induced NET formation.
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An increased CK activity was
2019-09-11
An increased CK2 activity was found in septal neuronal Astemizole dissected from rat embryos after hypoglycemia [36].
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br Acknowledgements This study was financially supported by
2019-09-10
Acknowledgements This study was financially supported by the National Special Research Programs for Non-Profit Trades (Agriculture) (Grant No. 201303045) and the Basic Foundation for Scientific Research of the State-level Public Welfare Institutes of China (Grant No. 2013JB10).
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Due to the results of the experiment we
2019-09-09
Due to the results of the experiment we decided to deploy our cloud service infrastructure with two platform-independent servers instead of one or three.
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br E E backside interaction The E possesses
2019-09-07
E3–E2 backside interaction The E2 possesses an important regulatory interface which is termed its backside as it is opposite to the catalytic cleft that bears the active-site cysteine forming the thioester with SUMOD.
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The excitatory amino acid L
2019-09-06
The excitatory amino KU 55933 L-glutamate or glutamate mediates most of the excitatory neurotransmission within the mammalian central nervous system (CNS) and has been implicated in numerous peripheral nervous system (PNS) pathways.
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br Materials and Methods br Results br Discussion
2019-09-05
Discussion The spatial properties of receptor-ligand interactions can influence receptor activation and signal propagation, but studying this phenomenon requires the development of systems capable of recapitulating complex biophysical traits.
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CD is a key co stimulation surface marker that
2019-09-04
CD28 is a key co-stimulation surface marker that can be detected in all peripheral T XMD8-92 in newborns, and the proportion of CD28bearing T cells reduces progressively with age [reviewed by (Fagnoni et al., 1996; Weng et al., 2009)].
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For immobilization of enzymes natural polymers
2019-09-03
For immobilization of enzymes, natural polymers depict several outstanding features as support.
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