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The proliferation of CCA cell lines can be stimulated by
2020-06-01
The proliferation of CCA cell lines can be stimulated by estrogen and other growth factors (Alvaro et al., 2006; DeMorrow, 2009; Mancino et al., 2009). It has also been reported that estrogen positively modulates cholangiocyte proliferation, which is associated with cholangiopathies found in humans
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2 ag sale br Experimental br Results and discussion On the
2020-06-01
Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it 2 ag sale is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of the conversio
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To better understand the mechanism
2020-05-29
To better understand the mechanism of splicing in CLCN1, we began by constructing a minigene spanning exons 5–7 of CLCN1, resulting in the synthetic CLCN1 (5–7) minigene. We also established a new assay using real-time reverse transcription (RT)-PCR, which can distinguish between splicing variants b
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Many researchers studied the experimental investigation
2020-05-29
Many researchers studied the experimental investigation of RHA in cement enhances the strength and durability of the concrete [9], [10], [11], [12]. It is most important that concrete must withstand its strength even after it is being exposed to any corrosive environment over a period of time. In ad
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Fujimoto et al pointed out that RPN knockout alleviated the
2020-05-29
Fujimoto et al. pointed out that RPN2 knockout alleviated the resistance of GC TNF-alpha, recombinant rat protein (MKN74 and KATO III) to docetaxel and DDP [23]. Yuan et al. demonstrated that the depletion of RPN2 resulted in the reduction in resistance of GC cells to drugs such as irinotecan, docet
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Interestingly global EGFR depletion increased the rate of ce
2020-05-29
Interestingly, global EGFR depletion increased the rate of cell elimination everywhere in the notum (Figures 2B–2D), irrespective of the deformation status of the cells. Accordingly, we found that Protein A/G receptor are not any more sensitive to stretching upon EGFR depletion (Figures S6A–S6C; Vid
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FRAX486 sale br Author Contributions br Acknowledgments This
2020-05-29
Author Contributions Acknowledgments This work was supported, in part, by a grant from the National Cancer Institute of the National Institutes of Health under Grant U01CA202241 and National Institutes of Health under Grant R01NS083856. Introduction The Eph (erythropoietin-producing human
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br Conclusion In this study we investigated functional
2020-05-29
Conclusion In this study, we investigated functional alterations of ECs following exposure to mechanical and/or physicochemical stimuli. Specifically, hypoxia induced phosphorylation with significant increases after 30 min and the maximum increase was after 180 min. Our data show that a combinati
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br DNA PK After sensing and binding to
2020-05-29
DNA-PK After sensing and binding to the DSB, Ku quickly recruits DNA-PKcs to the site of the DNA break. Similar to Ku70/80, recruitment of DNA-PKcs to DSBs occurs within seconds of their creation [12]. The interaction between Ku70/80 and DNA-PKcs requires the presence of dsDNA and the complex for
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In the belief that DNA
2020-05-29
In the belief that DNA-based nanosensors and DNA microarrays should be easier to operate, faster, more accurate and more economically viable than PCR-based techniques, an electrochemical DNA biosensor was designed for detection of G. boninense[9], [10]. This was developed based on a gold electrode m
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The DDR mediated lysyl oxidase induction in osteoblasts
2020-05-29
The DDR2-mediated lysyl oxidase induction in osteoblasts reported here is a novel function for this receptor. Various functions have been reported for DDR2. In an in-vitro study, Zhang and colleagues showed that DDR2 activation leads to Runx2 phosphorylation, which regulates osteoblast differentiati
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Data from our in vitro studies using
2020-05-29
Data from our in vitro studies using BEAS-2B cells showed a biphasic response of cells to NNK. The initial phase of decrease in CRM1 expression in NNK-exposed cells was observed in our previous study. In this study, we further showed that p-p53 (Thr55) expression was also decreased during this initi
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Interferon IFN induces formation of a heterotetrameric IFN g
2020-05-28
Interferon (IFN)-γ induces formation of a heterotetrameric, IFN-gamma-activated inhibitor of translation (GAIT) complex in human monocytic AZD3264 (Mazumder et al., 2003a, Sampath et al., 2004). The complex binds a bipartite stem-loop element in the 3′UTR of vascular endothelial growth factor (VEGF)
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According to these results the
2020-05-28
According to these results, the power GaN seems more robust than existing technologies (VDMOS, Superjunction, IGBT,) [5,10] and [11]. Comparing with the SiC technology, the previous works show a low SEE tolerance [[12], [13], [14]] and [15]. The SOA of power GaN devices can be equivalent to the IGBT
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To our knowledge this study is
2020-05-28
To our knowledge, this study is the first to construct a whole-body transcriptome of D. variabilis. Most of the data currently accessible in NCBI are derived from a midgut EST database consisting of 1679 transcripts (Anderson et al., 2008) and about 20,000 mRNA sequences from the testis-vas deferens
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