• br Conclusions br Acknowledgments This study was supported b

  2021-09-26

  

  Conclusions Acknowledgments This study was supported by funds from the National Natural Science Foundation of China (NSFC 31360245, 31460258) and the Applied Basic Research Foundation of Yunnan Province of China (2011FZ111). Introduction Acute myocardial infarction is the undoubted cause o

• Most studies to date have focused on

  2021-09-26

  

  Most studies to date have focused on the physiological functions of FPS in plants. As mentioned above, numerous factors affect FPS expression and FPS function. However, FPS enzymatic assays require radiolabeled substrate and thus detailed enzymatic characterizations of FPS, including substrate speci

• A previous study from our institution showed moderate correl

  2021-09-26

  

  A previous study from our institution showed moderate correlation between the APTT and Anti-FXa assays, prompting an institution-wide change to an Anti-FXa based monitoring of unfractionated heparin. The current study is a descriptive analysis to evaluate the clinical outcomes in this pediatric coho

• In spite of decades of research the mechanisms of SV

  2021-09-26

  

  In spite of decades of research the mechanisms of SV endocytosis and recycling remain controversial. Accumulating evidence suggests that SV endocytosis occurs by more than one mechanism (e.g. clathrin-independent endocytosis, clathrin-mediated endocytosis, bulk endocytosis; reviewed in (Dittman and

• Analgesic activity was evaluated by measuring

  2021-09-26

  

  Analgesic activity was evaluated by measuring tail flick latencies to the immersion of rat’s tail in water, maintained at ∼51°C [18] after recovery from anesthesia. Typically, rats were immobilized inside a restrainer, leaving only the tail exposed, which was then immersed into the hot water bath,

• br Introduction As a fundamental

  2021-09-26

  

  Introduction As a fundamental metal-dependent hydrolytic enzyme, inorganic pyrophosphatase (PPase) exhibits a specific catalytic ability, in which one molecule of inorganic pyrophosphate (PPi) can be transformed into two orthophosphate (Pi) ions [1,2]. The process of transformation is extremely e

• Evidence demonstrating the interplay between

  2021-09-26

  

  Evidence demonstrating the interplay between hypoxia and the dynamics of histone methylation is mounting [15], [43]. For example, hypoxia leads to an increase in H3K4me3 by inhibiting their responsible demethylase [44]. Hypoxia also leads to an increase in H3K9me2 by upregulating the methyltransfera

• br Histamine and glycaemia Histamine is involved in a

  2021-09-26

  

  Histamine and glycaemia Histamine is involved in a wide variety of pathophysiological events mostly related to the inflammatory response through four receptors, namely H1-4Rs. The first studies of Progesterone australia and diabetes date back to the 1950s. Since that time the involvement of hist

• In addition to lifestyle factors genetic factors

  2021-09-26

  

  In addition to lifestyle factors, genetic factors may also influence the efficacy of antineoplastic drugs in breast cancer patients.16, 17 The HER2 gene contains several single nucleotide polymorphisms (SNPs). Two of the most investigated HER2 SNPs are Ile655Val (rs1136201) and Ala1170Pro (rs1058808

• br Material and methods br Results br Discussion Liver

  2021-09-26

  

  Material and methods Results Discussion Liver plays a key role in the metabolism and detoxification of DON (Peng et al., 2017). However, various DON investigations generated inconsistent results, with some showing hepatotoxicity of DON, while others not. For example, one report stated that

• br Introduction The Ras superfamily of

  2021-09-24

  

  Introduction The Ras superfamily of small GTPases is composed of more than 150 protein members involved in a wide variety of biological processes, such as proliferation, differentiation, cytoskeletal organization, and protein trafficking [1]. The Ras superfamily proteins act as molecular switches

• For a long time the mechanism for the TG

  2021-09-24

  

  For a long time, the mechanism for the TG-lowering effect of nicotinic IFN-alpha 1, human recombinant protein mg has been thought that the lowered NEFA substrate from adipose tissue limits TG production from the liver (so-called NEFA hypothesis) [[1], [2], [3], [4]]. However, recent emerging eviden

• Contradictory results have been described

  2021-09-24

  

  Contradictory results have been described regarding the role of the Shh pathway during vertebrate skeletal myogenesis. Different studies have shown that Shh can increase or inhibit myoblasts proliferation and terminal muscle differentiation, depending on the experimental model [[1], [2], [3], [4], [

• When PKC was applied alone it attenuated the

  2021-09-24

  

  When PKC19–31 was applied alone, it attenuated the activity run-down following excision. Furthermore, the activity induced by addition of PKC19–31 during PMA treatment in many cases was higher than in controls. Accordingly, in our experimental conditions, the mechanism which underlays channel inhibi

• Nepicastat HCl We have presented evidence that only muscle F

  2021-09-24

  

  We have presented evidence that only muscle FBPase is detectable within HL-1 cells. This is consistent with past findings of the Eschrich's group, which showed that in rat heart Nepicastat HCl expression of FBPase is almost exclusively limited to the muscle isozyme [3]. Results of our preliminary

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