• Another possible explanation of the increased BOP

  2025-03-01

  

  Another possible explanation of the increased BOP levels might be excess cement. In the present study, cement-retained fixed restorations were used. Cementation of the implant-supported restorations may cause the insufficient removal of excess cement from the peri-implant sulcus. Also, the placement

• The chronic induction of skeletal muscle

  2025-03-01

  

  The chronic induction of skeletal muscle AMPK activity is an attractive therapeutic approach for DMD, as it addresses multiple cellular pathways needed for powerful phenotypic plasticity, including activation of the slow oxidative myofiber program, corrective autophagic signaling, as well as regulat

• The importance of TARPs for AMPAR expression and

  2025-03-01

  

  The importance of TARPs for AMPAR expression and function was revealed initially in the cerebellum, where the lack of γ-2 in the mutant mice waggler and stargazer (stg/stg) was associated with a selective loss of AMPAR-mediated synaptic currents in cerebellar granule atp enzyme (Chen et al., 2000;

• A large number of aldose reductase

  2025-03-01

  

  A large number of aldose reductase inhibitors have been prepared synthetically, and a limited number of them are therapeutically used. However, none of them is satisfactory. Here, Cannabis extracts with high content of non-psychotropic phytocannabinoids CBD/CBDA or CBG/CBGA showed statistically sign

• As regards feeding the ability

  2025-03-01

  

  As regards feeding, the ability to dissipate surplus energy in the form of heat is beneficial for animals if the protein concentration in the food is low, since it allows them then to meet the adequate protein intake requirement without getting fat. Some of the major dietary activators of the AHR ar

• Biotin-azide In earlier experiments on snails a behavioral m

  2025-03-01

  

  In earlier experiments on snails, a behavioral model was employed of certain food rejection to study the mechanisms of the reconsolidation of long-term associative memory. It was found that conditioned food stimuli (reminder) presentation, combined with injections of NMDA glutamate receptor antagon

• Our in vitro data show that CyaA does

  2025-03-01

  

  Our in vitro data show that CyaA does not play a critical role in the bacterial adherence to mammalian cells. This observation is in contrast to previous studies that reported a role for CyaA in FHA-mediated adherence of B. pertussis bacteria to the respiratory epithelial biotin 100 mg [37,38]. Thi

• Introduction Myasthenia gravis MG is an autoimmune

  2025-03-01

  

  Introduction Myasthenia gravis (MG) is an autoimmune disorder characterized by muscle weakness, which is mainly due to autoantibodies reducing the number or function of postsynaptic BIRB796 receptors (AChRs) [1], [2]. Animal models have been developed to uncover the immunopathogenesis of MG. Exper

• The mechanism by which Gas prevents inflammation

  2025-02-28

  

  The mechanism by which Gas6 prevents inflammation has been reported to be via inhibition of Toll-Like receptors (TLRs) signaling (Cui et al., 2016). After injury, TLRs become stimulated, leading to downstream activation of TRAF3 and TRAF6 and translocation of several transcription factors, such as I

• br Studies in zebrafish vascular and neural

  2025-02-28

  

  Studies in zebrafish: vascular and neural development and the regulation of left–right asymmetry Zebrafish embryos represent an excellent model system to examine vertebrate vascular development. Major advantages of the zebrafish system include its genetic tractability, small size, external fertil

• To identify the kinase s

  2025-02-28

  

  To identify the kinase(s) mediating H3.3S31 phosphorylation, we devised a 96-well-plate-compatible immunostaining assay, with Nogo-66 (1-40) specific for H3.3S31ph, and utilized it to screen both a Qiagen siRNA library covering 720 human kinases and a kinase inhibitor library (Selleck) containing 1

• br Mechanisms of homeostasis At face value

  2025-02-28

  

  Mechanisms of homeostasis At face value, homeostatic mechanisms may seem like nothing more than a simple balance between opposing forces; however, the ability of Mec1/Tel1 to each orchestrate both negative and positive regulation greatly complicates the system under consideration and argues again

• br Conflict of interest br Introduction Platelets are

  2025-02-28

  

  Conflict of interest Introduction Platelets are anucleate blood cells essential for hemostasis and wound healing; tight regulation of platelet numbers is crucial for human health. Platelets are synthesized and released from bone marrow megakaryocytes into the circulation where they remain for

• The results of our in vivo experiments provide promising evi

  2025-02-28

  

  The results of our in vivo experiments provide promising evidence that the apelin/APLNR axis is implicated in CCA growth and that targeting this axis with a receptor specific antagonist may help develop effective, tumor directed therapies. Not only do we show decreased proliferation and angiogenesis

• br Experimental section br Acknowledgements The authors than

  2025-02-28

  

  Experimental section Acknowledgements The authors thank Prof. Yongbing Cao from School of Pharmacy, the Second Military Medical University, for providing the fluconazole-resistant strains of Candida albicans(strain 100 and strain 103). This work was supported by Program for Innovative Research

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